Normally, it is harmless for healthy people to take caffeine. However, if you are taking certain drugs, be careful when drinking caffeinated drinks. Zithromax is a variety of antibiotics, including a pack of six 250 mg tablets, commonly known as A" Z-PAK. Although caffeine is not known to have a serious interaction with this antibiotic, there are some reasons why you may avoid taking caffeine when taking it. Medication.
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Increased caffeine content
Liver decomposes caffeine through cytochrome P-450 oxidase system. This process breaks down many drugs to prevent chemicals from accumulating in your blood. Paclitaxel and caffeine are decomposed in your liver in the same way. If you start using z-pak and then consume caffeine, it will reduce your ability to metabolize caffeine. This leads to an increase in circulating caffeine in the blood. According to the author of Drug Metabolism: Current Concepts, this result increases your risk of side effects such as irregular heart rates.
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Reduced efficacy
If you drink caffeinated beverages regularly, it is beneficial to stop drinking before you start using Z-PAK. According to Paul Ortiz de montellano, author of cytochrome p450: structure, mechanism and biochemistry, taking caffeine regularly and then starting to take z-pak can reduce the efficacy of the drug. This is because the same liver pathway is needed to decompose. Two drugs. Disrupting the effectiveness of antibiotics increases the risk of bacterial growth, which endangers your recovery.
According to a review published in the September 2006 Journal of Pharmacology and Therapy, caffeine suppressing immunity affects your immune system. If you are prescribed antibiotics, such as Z-PAK, caffeine intake may damage your own resistance. Infected. This review reports that caffeine can inhibit antibody and lymphocyte production. Both of these cells are necessary for resistance to infection.
Notes
Discuss with your doctor the risk of caffeine intake when taking z-pak. Since caffeine may have immunosuppressive effects, it may be a good idea to avoid caffeine in the first symptom of infection. If you choose to drink caffeine anyway, pay attention to your symptoms. If you feel palpitation or nervousness, reduce your consumption. This may be due to Z-PAK, a sign that your body metabolizes caffeine more slowly.