Kidney and B12


Vitamin B-12 is a macromolecule involved in many bodily processes, such as the production of blood cells and the function of the nervous system. Your kidneys are involved in absorbing B-12 and other vitamins to prevent them from escaping through urination. Diseased and malfunctioning kidneys are poorly absorbed, resulting in vitamin deficiency. For patients with chronic kidney disease, some synthetic B-12 is safer than others.

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span= "article-image inner caption-class"> vitamin B-12 is one of the eight B vitamins. (Picture: jupiterimages/ images)

Human body needs vitamin B-12 to synthesize DNA and RNA, produce red blood cells, transmit neuroelectric information, stimulate metabolism and regulate brain function, especially Short item memory. According to pregnancy and breastfeeding, the recommended daily B-12 for adults is 2.4 to 2.8 micrograms. Unlike most other B vitamins, which are endocrine in a few days, B-12 is usually stored in the body for months or years, and does not need to consume too much B-12 regularly. However, some conditions, such as pernicious anemia, can lead to poor absorption of B-12.

Kidney absorption and storage is responsible for filtering many nutrients from blood and lymph, including vitamin B-12 and other B vitamins, such as folic acid. According to a study published in the medical journal Renal Physiology in 2006, besides vitamin preservation, the absorption of renal tubules is also important for vitamin metabolism, storage and homeostasis. For people with chronic renal failure or acute renal injury, the absorption of renal tubules is very important for vitamin metabolism, storage and homeostasis. 。 Her vitamin and other nutrient levels are usually excreted through urine. High levels of homocysteine in the blood indicate that you have very little sulfur. Homocysteine damages blood vessels and is associated with cardiovascular disease.

Potential toxicity

Natural form of B-12 in animal food-39; s is called cobalamin, which is actually non-toxic and has nothing to do with any serious side effects. However, the synthesized B-12 is potentially toxic at high doses and may trigger allergic reactions. The most common B-12 supplement on the market is cyanocobalamin, which forms cyanide, a neurotoxin, as a by-product. Such a small amount of cyanide does not pose a major threat to the health of the liver and kidneys, but for those with organ dysfunction, the risk is magnified. The diseased kidney cannot detoxify cyanide to thiocyanate, which is harmless and easy to discharge.

suggests that people with chronic kidney disease have a higher risk of B-12 deficiency, so supplementation may be necessary. However, cyanocobalamin has a slightly higher risk for kidney patients, so other forms such as mecobalamin, cobalamin hydrochloride or cobalamin adenosine may be safer options. The therapeutic dose of B-12 was between 500 and 1000 micrograms. If you take oral supplements, place the tablets under your tongue for better absorption.